| Methods |
Randomized, double‐blind, placebo‐controlled.
Weight loss trial. |
| Participants |
220 patients with controlled HTN. 15% African American. 52 week follow‐up. Mean age 51 y. Mean BMI 33.9 kg/m2. Mean weight 98 kg. US. |
| Interventions |
Sibutramine 20 mg daily (n=146). Attrition rate 42%.
Placebo (n=74). Attrition rate 51%. |
| Outcomes |
weight loss, 5% and 10% responders, BMI, waist circ, waist‐hip ratio, lipid profile, blood pressure, heart rate |
| Notes |
Co‐intervention: diet counseling |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment? |
Unclear risk |
B ‐ Unclear |
