| Methods |
Randomized, double‐blind, placebo‐controlled.
Weight loss trial. |
| Participants |
86 patients with DM2 on sulfonylurea treatment. 52 week follow‐up. Mean age 47 y. Mean BMI 30 kg/m2. Mean weight 74 kg. Mexico |
| Interventions |
Sibutramine 10 mg daily (n=44). Attrition rate 45%.
Placebo (n=42). Attrition rate 45%. |
| Outcomes |
weight loss, 5% and 10% responders, waist circ, lipid profile, A1c, uric acid, glucose, blood pressure, heart rate |
| Notes |
Co‐interventions: diet and exercise counseling |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment? |
Unclear risk |
B ‐ Unclear |
