10. Results by individual review: prevention and management of infection.
| Insecticide‐treated nets for preventing malaria (Gamble 2006) | |||
| Comparison | Outcome | No. of studies, no. women | Results |
| Insecticide‐treated nets vs no nets (all) | Fetal loss | 5 studies | RR 0.68, 95% CI 0.48 to 0.98 (P = 0.04), reduction in fetal loss for women receiving intervention of insecticide‐treated nets GRADEa: low |
| Insecticide‐treated nets vs no nets (First or second pregnancy) | Fetal loss | 4 studies | RR 0.67, 95% CI 0.47 to 0.97 (P = 0.03), reduction in fetal loss for first or second pregnancy for women receiving intervention of insecticide‐treated nets GRADEa: low |
| Insecticide‐treated nets vs no nets (Fifth or greater pregnancy) | Fetal loss | 1 study | RR 1.02, 95% CI 0.17 to 6.23, no evidence of a difference GRADEa: very low |
| Insecticide‐treated nets vs no nets (all) | LBW | 4 studies | RR 0.80, 95% CI 0.64 to 1.00 (P = 0.05), a possible reduction |
| Insecticide‐treated nets vs no nets (First or second pregnancy) | LBW | 3 studies | RR 0.77, 95% CI 0.61 to 0.98 (P = 0.03), reduction in LBW for first or second pregnancy for women receiving intervention of insecticide‐treated nets |
| Insecticide‐treated nets vs no nets (Fifth or greater pregnancy) | LBW | 1 study | RR 1.12, 95% CI 0.56 to 2.24, no evidence of a difference |
| Insecticide‐treated nets vs no nets | SGA | Outcome not reported | |
| Insecticide‐treated nets vs no nets | NICU admission | Outcome not reported | |
| Drugs for preventing malaria (Radeva‐Petrova 2014) | |||
| Comparison | Outcome | No. of studies, no. women | Results |
| Preventive antimalarials vs placebo/no intervention (women of all parity groups) | Stillbirth | 5 studies, 7130 women | RR 1.02, 95% CI 0.76 to 1.36, evidence of no difference GRADEb: moderate |
| Preventive antimalarials vs placebo/no intervention (women in first or second pregnancy) | Stillbirth | 4 studies, 2703 women | RR 0.97, 95% CI 0.63 to 1.49, no evidence of a difference GRADEb: low |
| Preventive antimalarials vs placebo/no intervention (women of all parity groups) | Perinatal death | 4 studies, 5216 women | RR 1.24, 95% CI 0.94 to 1.63, evidence of no difference GRADEb: moderate |
| Preventive antimalarials vs placebo/no intervention (women in first or second pregnancy) | Perinatal death | 2 studies, 1620 women | RR 0.73, 95% CI 0.54 to 1.00 (P = 0.05), no evidence of a difference GRADEb: low |
| Preventive antimalarials vs placebo/no intervention (women of all parity groups) | LBW | 4 studies, 3644 women | RR 1.06, 95% CI 0.89 to 1.27, no evidence of a difference |
| Preventive antimalarials vs placebo/no intervention (women in first or second pregnancy) | LBW | 10 studies, 3619 women | RR 0.73, 95% CI 0.61 to 0.87 (P = 0.00065), reduction in LBW for women receiving preventive antimalarials |
| Preventive antimalarials vs placebo/no intervention | SGA | Outcome not reported | |
| Preventive antimalarials vs placebo/no intervention | NICU admission | Outcome not reported | |
| CI: confidence interval; IUGR: interuterine growth restriction; LBW: low birthweight; NICU: neonatal intensive care unit; RR: risk ratio; SGA: small‐for‐gestational age | |||
aGRADE assessed by review overview authors because it was not reported in the original review; bGRADE rating reported in the original review.