Comparison 1. Thromboembolic events.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1.1 Self‐monitoring and self‐management	18	7594	Risk Ratio (M‐H, Fixed, 95% CI)	0.58 [0.45, 0.75]
1.1.1 Self‐management	11	3497	Risk Ratio (M‐H, Fixed, 95% CI)	0.47 [0.31, 0.70]
1.1.2 Self‐monitoring	7	4097	Risk Ratio (M‐H, Fixed, 95% CI)	0.69 [0.49, 0.97]
1.2 Events by Clinical Condition	17	4809	Risk Ratio (M‐H, Fixed, 95% CI)	0.52 [0.38, 0.71]
1.2.1 Mechanical Valve	6	1816	Risk Ratio (M‐H, Fixed, 95% CI)	0.53 [0.32, 0.90]
1.2.2 Atrial Fibrillation	1	202	Risk Ratio (M‐H, Fixed, 95% CI)	0.33 [0.01, 8.09]
1.2.3 Any indication	10	2791	Risk Ratio (M‐H, Fixed, 95% CI)	0.51 [0.34, 0.77]
1.3 Events by Self‐management (sensitivity)	13	4558	Risk Ratio (M‐H, Fixed, 95% CI)	0.50 [0.36, 0.69]
1.3.1 Self‐management	9	3618	Risk Ratio (M‐H, Fixed, 95% CI)	0.45 [0.30, 0.66]
1.3.2 Self‐monitoring	4	940	Risk Ratio (M‐H, Fixed, 95% CI)	0.63 [0.36, 1.09]
1.4 Events by specialty	16	7344	Risk Ratio (M‐H, Fixed, 95% CI)	0.60 [0.46, 0.78]
1.4.1 Specialised Care	8	4947	Risk Ratio (M‐H, Fixed, 95% CI)	0.63 [0.44, 0.90]
1.4.2 Primary Care	8	2397	Risk Ratio (M‐H, Fixed, 95% CI)	0.56 [0.38, 0.84]