Skip to main content
. 2016 Jul 5;2016(7):CD003839. doi: 10.1002/14651858.CD003839.pub3
Date Event Description
1 June 2016 New search has been performed The search was updated in July 2015. Ten new trials were found for inclusion.
1 June 2016 New citation required and conclusions have changed The original review reported a reduction in mortality with self‐management or self‐monitoring; in this update, with the addition of the 10 new trials (adding 4227 participants) this risk reduction was no longer statistically significant; however, after the removal of low‐quality studies, the original finding of a reduction in all‐cause mortality was found.
Secondly, the original review found that trials of self‐monitoring alone did not result in a statistically significant reduction in thromboembolic events; the new finding is a statistically significant reduction.
Thirdly, in the original review, self‐monitoring significantly reduced major haemorrhage; in this update, self‐monitoring did not reduce major haemorrhage, but removal of studies with low quality resulted in a statistically significant reduction.
27 March 2012 Amended Feedback added
7 March 2012 Amended Add information about external funding sources.
25 May 2010 Amended Amended Figure 4 ‐ GRADE table.