Fitzmaurice 2002.

Study characteristics
Methods	Multicentre, randomised controlled trial.
Participants	Participants were ambulatory adults aged > 18 years attending an anticoagulation clinic, receiving anticoagulation therapy for > 6 months, judged as capable of self‐management, and with satisfactory INR control (n = 56). The study was based in six general practices that used the Birmingham model of anticoagulation management (West Midlands, UK).
Interventions	Self‐management vs usual care Participants were randomised to: a) self‐management (n = 30): self‐testing using Coaguchek® device and self‐adjustment of dosing. Testing was performed every 2 weeks or after 1 week following dosage adjustment. b) conventional management (n = 26) in practice clinics.
Outcomes	Primary and secondary outcomes were not specified. Data were reported for: percentage time in INR range; adverse events; frequency of testing; costs; quality of life.
Trial identification
Study duration	6 months
Oral anticoagulant used	Warfarin
Notes	Participants in the intervention group attended two 1‐2 hour duration educational workshops on anticoagulation self‐management. Workshops were based within individual practices, were organised by research staff and attended by practice staff.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Computer‐generated coding
Allocation concealment (selection bias)	Low risk	Concealment of allocation was not reported, contact with author led to information on appropriate method of concealment
Intention to treat analysis	High risk	ITT analysis was not performed
Reporting of losses of follow‐up	Low risk	7/56 (12.5%) of participants were lost to follow‐up; reasons reported
Blinding	High risk	Participants and study staff were not blinded to the intervention