Gardiner 2005.

Study characteristics
Methods	Single centre, randomised controlled trial.
Participants	Participants (n = 84) were adults aged > 18 (mean 58) years who had received anticoagulation therapy for > 8 months and had a record of good compliance. The study was based in an anticoagulation clinic in University Hospital (London, UK).
Interventions	Self‐monitoring vs usual care Participants were randomised to: a) self‐testing (n = 44) using the Coagucheck® monitoring device once per week b) control (n = 40), receiving usual care by visiting the hospital anticoagulation clinic for testing every 4 weeks.
Outcomes	Primary and secondary outcomes were not specified. Data were reported for: Major and minor bleeding, thromboembolism and mortality, percentage of time within target range, and acceptability.
Trial identification
Study duration	6 months
Oral anticoagulant used	Not reported
Notes	The intervention group attended two training sessions.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Randomisation sequence generation was not reported
Allocation concealment (selection bias)	Unclear risk	Concealment of allocation was not reported
Intention to treat analysis	High risk	ITT analysis was not performed
Reporting of losses of follow‐up	Low risk	15/84 (17.9%) of participants were lost to follow‐up; reasons were reported
Blinding	High risk	Participants and study staff were not blinded to the intervention