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. 2021 Jan 27;39(7):807–821. doi: 10.1200/JCO.20.01359

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© 2021 by American Society of Clinical Oncology

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FIG 1. — Relapse patterns for SJMB03 and SJYC07 patients with medulloblastoma. (A) Overview of trial designs and risk stratifications. (B) Apparent relapse rates by medulloblastoma subgroup per trial. (C) Medulloblastoma subgroup distributions per trial risk stratifications. Time to relapse by subgroup for (D) SJMB03 patients and (E) SJYC07 patients. (F) Anatomic patterns of relapse per subgroup for SJMB03 and (G) SJYC07 patients. CSI, craniospinal irradiation; DNMB, desmoplastic nodular medulloblastoma; GTR, gross total resection; HDMTX, high-dose methotrexate; MB, medulloblastoma; RT, radiation therapy; SHH, sonic hedgehog; TTR, time to relapse; UC, unclassified; VCR, vincristine; WNT, wingless.