Skip to main content
. 2021 Jan 27;39(7):807–821. doi: 10.1200/JCO.20.01359

FIG 4.

FIG 4.

Molecular landscape of relapsed medulloblastoma. (A) Oncoprint depicting patient characteristics, driver gene alterations, and chromosomal copy number variation for patient-matched tumor pairs with available next-generation sequencing (n = 57 patients). (B) Compartment-specific patterns of driver gene alterations by molecular subgroup. (C) Genomic track of chromosome 2 depicting alteration patterns observed for MYCN. (D) Compartment-specific patterns of chromosome arm copy number variation by molecular subgroup for patient-matched tumor pairs (n = 107 patients). Genomic tracks depicting alteration patterns of (E) chromosome 17 and (F) chromosome 10. CNV, copy number variation; G3, Group 3; G4, Group 4; MB, medulloblastoma; SHH, sonic hedgehog; SNV, single nucleotide variant; WES, whole-exome sequencing; WNT, wingless.