Forrest plot showing subgroup analyses of overall survival by risk factor and conditioning regimen (ITT population). ALL, acute lymphoblastic leukaemia; BM, bone marrow, CR1, first complete remission (below 5% of morphological blasts in bone marrow; no active extramedullary disease); CR2, second complete remission; CR3, third complete remission; HSCT, haematopoietic stem cell transplantation; MD, human leukocyte antigen (HLA)-compatible (nine or 10 out of 10 allelic matches) related or unrelated matched donor; MRD, minimal residual disease; MSD, HLA-identical sibling donor; TBI, total body irradiation.