Holt 1994.
| Methods | RCT conducted in non‐fluoridated areas in UK. | |
| Participants | 1099 out of the potential 2177 children aged 9 years old (who participated in the trial at 2 years old for a period of 3 years) gave positive consent to the follow‐up study. | |
| Interventions | Group 1: Fluoride toothpaste (550 ppm) (n = 568).
Group 2: Fluoride toothpaste (1000 ppm) (n = 531). A sample of children who did not participate in the trial formed a third group and not included in this review. |
|
| Outcomes | TFI. DDE Index. Both assessed from photographic digital images. | |
| Notes | Intra‐ and inter‐examiner reliability for TFI (Kappa = 0.68 and 0.78 respectively). Data for the third group not used within this review. |
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