Osuji 1988.

Methods	Case‐control study conducted in a fluoridated community in Canada.
Participants	633 children aged 8, 9 and 10 years old screened for fluorosis and 177 interviewed and 139 with full data available for analysis.
Interventions	Case: fluorosis index score >0 (n = 65). Control: the next non‐case of the same age and sex in the classroom (n = 74). Exposure: professional application of fluoride; early use of fluoride mouthrinses; early use of fluoride toothpaste during the child's first 5 years.
Outcomes	TFI. Photographic assessment.
Notes	Intra‐examiner reliability (Kappa = 0.93). Small discrepancies in the ORs estimates used in the review (generated by RevMan) compared to the original study.