Brigliadori 2016.

Study characteristics
Study design	Cohort
Study setting	Setting: Oncology Network of Romagna Country: Italy Dates: tumour samples collected between 2008 and 2013
Selection of participants	Participants had GBM treated with surgery and Stupp regimen. People undergoing biopsy were not included in our analysis.
Participant characteristics	Sample size: 105 (deaths: 73) Age: median 61, SD NR; range 23–76 years Sex: 61.9% men KPS: median NR; KPS ≤ 70: 19.1%, KPS: 80–90: 43.8%, KPS 100: 37.1%
Tumour characteristics	GBM: 100% First diagnosis: NR Biopsy: 0%; subtotal resection: 51.1%; total resection: 49% IDH1 wild‐type: NR; IDH2 wild‐type: NR
Treatment regimen	Stupp protocol
MGMT promoter methylation tests implemented	PSQ, Bead array
Dates and follow‐up	Timing of MGMT assessment: at diagnosis Start time for follow‐up: date of diagnosis; follow‐up: median 55; range 5–79 months
Notes