Karayan‐Tapon 2010.

Study characteristics
Study design	Cohort
Study setting	Setting: Centres in Poitiers, Rennes and Nantes Country: France Dates: NR
Selection of participants	Participants had GBM treated with surgery and Stupp regimen
Participant characteristics	Sample size: 81 (deaths: NR) Age: median 61; range 30–78 years Sex: 55.6% men KPS: median NR; WHO performance status: 0–2: 52/81 (64.2%); WHO performance status 3–4: 23/81 (28.4%); WHO performance status not available: 6/81 (7.4%)
Tumour characteristics	GBM: 100% First diagnosis: 100% Biopsy: NR; subtotal resection: NR; total resection: NR; extent of resection determined perioperatively by neurosurgeon IDH1 wild‐type: NR; IDH2 wild‐type: NR
Treatment regimen	Stupp protocol
MGMT promoter methylation tests implemented	MSP, PSQ, IHC, SQ‐MSP, PCR‐mRNA
Dates and follow‐up	Timing of MGMT assessment: at diagnosis Start time for follow‐up: date of surgery; follow‐up: median 16; range 5–57 months
Notes