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. 2021 Mar 12;2021(3):CD013316. doi: 10.1002/14651858.CD013316.pub2

McDonald 2013.

Study characteristics
Study design Cohort
Study setting Setting: Royal North Shore Hospital and the North Shore Private Hospital, Sydney
Country: Australia
Dates: NR
Selection of participants Retrospective cohort of people with primary GBM treated by gross total resection
Participant characteristics Sample size: 78 (deaths: 74)
Age: mean 58.4, SD 12.4; range 22–83 years
Sex: 75.6% men
KPS: NR
Tumour characteristics GBM: 100%
First diagnosis: 100%
Biopsy: 0%; subtotal resection: 0%; total resection: 100%
IDH1 wild‐type: 97.4%; IDH2 wild‐type: NR
Treatment regimen Concurrent radiotherapy and TMZ followed by adjuvant TMZ (61.5%) or TMZ as an adjuvant therapy after radiotherapy (38.5%)
MGMT promoter methylation tests implemented MSP, PSQ
Dates and follow‐up Timing of MGMT assessment: at diagnosis
Start time for follow‐up: NR; follow‐up: median NR; range NR
Notes