Melguizo 2012.

Study characteristics
Study design	Cohort
Study setting	Setting: Hospital Virgen de las Nieves from Granada (Spain) and the University Hospital of Sassari (Italy) Country: Spain and Italy Dates: tumour samples collected between 2001 and 2009
Selection of participants	Participants aged ≥ 70 years with newly diagnosed GBM and postoperative KPS ≥ 60
Participant characteristics	Sample size: 78 (deaths: NR) Age: mean 56; range 24–81 years Sex: 53.8% men KPS: median NR. All participants had KPS ≥ 60
Tumour characteristics	GBM: 100% First diagnosis: 100% Biopsy: NR; subtotal resection: NR; total resection: NR IDH1 wild‐type: NR; IDH2 wild‐type: NR
Treatment regimen	Concurrent chemoradiotherapy with TMZ followed by adjuvant TMZ
MGMT promoter methylation tests implemented	MSP, IHC
Dates and follow‐up	Timing of MGMT assessment: at diagnosis Start time for follow‐up: date of diagnosis; follow‐up: median NR; range NR
Notes