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. 2021 Mar 12;2021(3):CD013316. doi: 10.1002/14651858.CD013316.pub2

Nguyen 2015.

Study characteristics
Study design Cohort
Study setting Setting: Oncological Centre, University Hospital of Strasbourg
Country: France
Dates: cases treated and followed up between 2006 and 2010
Selection of participants Participants aged > 18 years with treatment‐naive GBM
Participant characteristics Sample size: 106 (deaths: NR)
Age: median NR, SD NR; aged ≥ 50 years: 78%, aged < 50 years: 22%
Sex: 63% men
KPS: NR
Tumour characteristics GBM: 100%
First diagnosis: 100%
Biopsy: 12%; subtotal resection: 34%; total resection: 34%; gross‐total (no residual tumour on MRI), subtotal (residual tumour on MRI)
IDH1 wild‐type: 98%; IDH2 wild‐type: NR
Treatment regimen Stupp protocol
MGMT promoter methylation tests implemented FSQ‐MS‐PCR
Dates and follow‐up Timing of MGMT assessment: at diagnosis
Start time for follow‐up: NR; follow‐up: median 17.4; range 2–92.8 months
Notes