Yamashita 2018.
Study characteristics | ||
Study design | Cohort | |
Study setting | Setting: Miyazaki University Hospital Country: Japan Dates: surgery between February 2008 and July 2015 |
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Selection of participants | People with newly diagnosed GBM who had undergone surgery | |
Participant characteristics | Sample size: 75 (deaths: NR) Age: median 64; range 32–84 years Sex: 61.3% men KPS: median NR; KPS 90–100: 18 (24%); KPS 70–80: 34 (45.3%); KPS < 70: 23 (30.7%) |
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Tumour characteristics | GBM: 100% First diagnosis: 100% Biopsy: 2.7%; subtotal resection: 30.7%; total resection: 66.7% 92% (IDH1 mutated 6.7%; unknown 1.3%); IDH2 wild‐type: NR |
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Treatment regimen | Stupp protocol | |
MGMT promoter methylation tests implemented | MSP, PCR‐HRM | |
Dates and follow‐up | Timing of MGMT assessment: tissue specimens obtained at surgery Start time for follow‐up: NR; follow‐up: median 17 months; range NR |
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Notes |