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. 2021 Mar 12;2021(3):CD013316. doi: 10.1002/14651858.CD013316.pub2

Yamashita 2018.

Study characteristics
Study design Cohort
Study setting Setting: Miyazaki University Hospital
Country: Japan
Dates: surgery between February 2008 and July 2015
Selection of participants People with newly diagnosed GBM who had undergone surgery
Participant characteristics Sample size: 75 (deaths: NR)
Age: median 64; range 32–84 years
Sex: 61.3% men
KPS: median NR; KPS 90–100: 18 (24%); KPS 70–80: 34 (45.3%); KPS < 70: 23 (30.7%)
Tumour characteristics GBM: 100%
First diagnosis: 100%
Biopsy: 2.7%; subtotal resection: 30.7%; total resection: 66.7%
92% (IDH1 mutated 6.7%; unknown 1.3%); IDH2 wild‐type: NR
Treatment regimen Stupp protocol
MGMT promoter methylation tests implemented MSP, PCR‐HRM
Dates and follow‐up Timing of MGMT assessment: tissue specimens obtained at surgery
Start time for follow‐up: NR; follow‐up: median 17 months; range NR
Notes