Term |
Meaning |
ablate |
to remove or otherwise destroy the biological function of any part (e.g. bone marrow) |
alkylating agent |
agents used in cancer treatment that attaches an alkyl group (CnH2n+1) (hydrocarbon) to DNA (molecule of cell nucleus) |
allogeneic |
denoting or relating to cells or tissues from individuals belonging to the same species but genetically dissimilar (and hence immunologically incompatible) |
antithymocyte globulin |
an infusion of horse or rabbit‐derived antibodies against human T cells which is used in the prevention and treatment of acute rejection in organ transplantation |
chromatography |
the collective term for a set of laboratory techniques for the separation of mixtures |
electrophoresis |
the motion of dispersed particles relative to a fluid under the influence of a spatially uniform electric field |
endogenous |
caused by factors inside the organism or system |
erythropoiesis |
the process by which red blood cells (erythrocytes) are produced |
gonadal failure |
the condition in which the production of sex hormones and germ cells are inadequate |
hemolytic anemia |
anemia due to the abnormal breakdown of red blood cells |
hemosiderosis |
a form of iron overload disorder resulting in the accumulation of hemosiderin which is an iron‐storage complex |
hepcidin |
a peptide hormone produced by the liver which is involved in the master regulation of iron homeostasis in humans and other mammals |
intramedullary |
a medical term meaning the inside of a bone |
iron chelation |
the process by which some molecules called chelator bind to iron and remove them as well as neutralise the toxic property (desferrioxamine) |
myeloablation |
the depletion of the bone marrow cells by the administration of high doses of chemotherapy or radiation therapy |
portal bridging |
a form of confluent necrosis between some areas of liver in chronic liver disease |
purine analogue |
anti‐metabolites which mimic the structure of metabolic purines (molecules in the cell nucleus) |