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. 2002 Jan 21;2002(1):CD002123. doi: 10.1002/14651858.CD002123

Thomas 1995.

Methods Not stated if random 
 Blinding unclear 
 Crossover design 
 31 women randomised, 29 analysed
Participants Inclusion: primary dysmenorrhoea, previous ineffective treatment with NSAIDs, contraindications to NSAIDs, gynaecological exam to rule out pathology, women with no previous use of TENS 
 Age: mean 30.2 (7.3) years 
 Location: Sweden
Interventions 7 treatments ‐ participants split into two groups: TENS or acupuncture 
 Duration: 20 min treatment, 7 days and 3 days prior to onset of menstruation every month 
 Acupuncture treatments: 
 different mode each month for 4 months then preferred treatment for 5th month 
 Location: 5 points, bladder 32 (back, bilateral), abdomen CV4, spleen 9 and 6 (legs) 
 1. manual stimulation at insertion, every 5 min 
 2. low‐frequency electrical stimulation at 2 Hz to evoke muscle contractions 
 3. high‐frequency 100 Hz, intensity adjusted to comfort level 
 4. periosteal stimulation (for 30 sec) 3 or 4 times for each point 
 TENS treatments: 
 3 different modes for 3 months, patients preferred treatment for 4th month, pulse duration 0.2 msec 
 Location: Thoracic 10 to Lumbar 1 
 1. Low‐frequency TENS, 2 Hz 
 2. High‐frequency TENS, 100 Hz 
 3. Placebo TENS
Outcomes Pain scale ‐ VAS 
 Blood loss 
 Nausea 
 Hours of work lost 
 Analgesics taken (no mention of type or dose) 
 Subjective assessment
Notes No information on the baseline similarities of the randomised groups
Risk of bias
Bias Authors' judgement Support for judgement
Adequate sequence generation? Unclear risk "randomised although serial order was maintained".
Allocation concealment? Unclear risk Unclear.
Blinding? 
 All outcomes Low risk Participants were blinded.
Incomplete outcome data addressed? 
 All outcomes Low risk All patients analysed.
Free of selective reporting? Low risk All relevant outcomes were reported.

OCP: oral contraceptive pill