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. 2021 Jan 15;2021(1):CD012768. doi: 10.1002/14651858.CD012768.pub3

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Copyright © 2021 The Authors. Cochrane Database of Systematic Reviews published by John Wiley & Sons, Ltd. on behalf of The Cochrane Collaboration.

This is an open access article under the terms of the Creative Commons Attribution-Non-Commercial Licence, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

PMC Copyright notice

The clinical pathway describes how patients might present and the point in the pathway at which they would be considered for testing with Xpert Ultra or Xpert MTB/RIF. This algorithm for the use of a molecular WHO‐recommended rapid diagnostic (WRD), which includes Xpert Ultra and Xpert MTB/ RIF, comes from the WHO operational handbook on tuberculosis (WHO Operational Handbook Diagnosis (Module 3) 2020). Copyright © [2020] [World Health Organization]: reproduced with permission.

Abbreviations: DST: drug susceptibility testing; INH: isoniazid; MDR‐TB: multidrug‐resistant TB; MTB: Mycobacterium tuberculosis; PLHIV: people living with HIV; RIF: rifampicin; TB: tuberculosis; WRD: WHO‐recommended rapid diagnostic, which includes Xpert Ultra and Xpert MTB/RIF.