7. Sensitivity analyses, Xpert Ultra in cerebrospinal fluid.
Type of specimen | Number of studies (specimens) | Pooled sensitivity (95% Crl) | Pooled specificity (95% Crl) | Predicted sensitivity (95% Crl) | Predicted specificity (95% Crl) |
All participants | 6 (475) | 89.4% (79.1 to 95.6) | 91.2% (83.2 to 95.7) | 53.0% (36.6 to 69.6) | 98.7% (97.5 to 99.5) |
Consecutive participant selection | 5 (471) | 87.9% (76.4 to 94.6) | 90.4% (81.1 to 95.1) | 88.0% (65.2 to 96.7) | 90.5% (65.5 to 97.7) |
Reference standard blinding | 4 (432) | 88.5% (74.7 to 95.6) | 89.1% (76.9 to 94.3) | 88.6% (63.4 to 97.2) | 89.2% (61.0 to 97.1) |
Single specimen per participant | 4 (432) | 88.5% (74.7 to 95.6) | 89.1% (76.9 to 94.3) | 88.6% (63.4 to 97.2) | 89.2% (61.0 to 97.1) |
Abbreviations: Crl: credible interval.