| Methods |
Method of randomisation unclear; unclear blinding status; ITT unclear |
| Participants |
Age 0.17 to 8.75 years (mean 2.46 years); both sexes; duration of illness before onset of therapy not clear |
| Interventions |
Experimental arm: ceftriaxone; control arm: ampicillin‐chloramphenicol |
| Outcomes |
Death; sensorineural deafness; hydrocephalus and blindness |
| Notes |
|
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Unclear risk |
Insufficient information about the sequence generation process |
| Allocation concealment (selection bias) |
Unclear risk |
Not reported |
| Blinding (performance bias and detection bias)
All outcomes |
Unclear risk |
The study did not address this |
| Incomplete outcome data (attrition bias)
All outcomes |
Low risk |
|
| Selective reporting (reporting bias) |
Low risk |
|
| Other bias |
Unclear risk |
Insufficient information |
