3. Meta‐regression analyses for chest CT of suspected cases.
| Test, analysis group | Studies (n) | Number of participants (cases) | Sensitivity (95% CI) | Specificity (95% CI) |
| Reference standard conduct | ||||
| RT‐PCR testing at least twice for all initial negative results | 9 | 2087 (1018) | 88.1% (78.5 to 93.8) | 71.3% (59.9 to 80.6) |
| RT‐PCR testing not repeated for all initial negative results | 22 | 11,344 (5779) | 86.7% (82.3 to 90.1) | 82.6% (77.8 to 86.6) |
| P value | 0.74 | 0.05 | ||
| Definition for index test positivity | ||||
| Radiologist impression | 13 | 7000 (3565) | 90.3% (84.5 to 94.1) | 77.2% (67.0 to 84.9) |
| Formal scoring system | 23 | 6805 (3333) | 85.9% (81.2 to 89.2) | 80.0% (75.0 to 84.2) |
| P value | 0.15 | 0.58 | ||
| CI: confidence interval;CT: computed tomography; RT‐PCR: reverse transcription polymerase chain reaction | ||||