15. Rates of mechanical ventilation in the intensive care unit.

Intervention/Comparison	Outcome	Illustrative comparative risks (95% CI)		Relative effect: risk ratio (95% CI)	Number of participants (studies)	Certainty of the evidence (GRADE)	Comments: overview authors' assessment of the certainty of evidence
		Assumed risk	Corresponding risk
		With comparator	With intervention
IV aminophylline + SABA + systemic steroids vs Placebo + SABA + systemic steroids (Mitra 2005)	Rates of patients mechanically ventilated in ICU	61 per 1000	6 per 1000 (1 to 100)	0.09 (0.01 to 1.64)	163 (1)	Very low	Certainty downgraded due to very serious imprecision and risk of bias in review (single author reviewed each abstract)

CI: confidence interval; GRADE: Grading of Recommendations Assessment, Development and Evaluation; ICU: intensive care unit; SABA: short‐acting beta2‐agonist.