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. 2021 Apr 13;11:630432. doi: 10.3389/fonc.2021.630432

Table 2.

Univariate and multivariate analyses for disease-free survival.

Univariate Multivariate
Variable HR 95% CI P value HR 95% CI P value
Age 0.594
 ≤40 vs >60 1.351 0.626–2.914 0.444
 40–60 vs >60 0.994 0.548–1.803 0.984
Menopausal status
 pre vs post 0.737 0.487–1.113 0.147
Differentiation
 II vs III 0.730 0.457–1.164 0.186
TNM stage 0.008 0.008
 II vs I 1.421 0.860–2.346 0.170 1.485 0.887–2.485 0.132
 III vs I 2.758 1.446–5.259 0.002 2.858 1.469–5.563 0.002
Molecular subtype 0.194 0.049
 Luminal B vs Luminal A 1.106 0.580–2.107 0.760 0.813 0.415–1.593 0.546
HER2-enriched vs Luminal A 0.986 0.497–1.956 0.967 0.701 0.337–1.458 0.342
Triple-negative vs Luminal A 1.626 0.930–2.843 0.088 1.493 0.849–2.626 0.164
miR-223
 low vs high 3.960 2.201–7.126 <0.001 3.789 2.098–6.843 <0.001

CI, confidence interval; HR, hazard ratio.

The covariates in the Cox model were all categorical variables, and the adjusted p value and HR were derived from the model.

The p value of the univariate analysis is marked bold.