Table 2.
Univariate | Multivariate | |||||
---|---|---|---|---|---|---|
Variable | HR | 95% CI | P value | HR | 95% CI | P value |
Age | 0.594 | |||||
≤40 vs >60 | 1.351 | 0.626–2.914 | 0.444 | |||
40–60 vs >60 | 0.994 | 0.548–1.803 | 0.984 | |||
Menopausal status | ||||||
pre vs post | 0.737 | 0.487–1.113 | 0.147 | |||
Differentiation | ||||||
II vs III | 0.730 | 0.457–1.164 | 0.186 | |||
TNM stage | 0.008 | 0.008 | ||||
II vs I | 1.421 | 0.860–2.346 | 0.170 | 1.485 | 0.887–2.485 | 0.132 |
III vs I | 2.758 | 1.446–5.259 | 0.002 | 2.858 | 1.469–5.563 | 0.002 |
Molecular subtype | 0.194 | 0.049 | ||||
Luminal B vs Luminal A | 1.106 | 0.580–2.107 | 0.760 | 0.813 | 0.415–1.593 | 0.546 |
HER2-enriched vs Luminal A | 0.986 | 0.497–1.956 | 0.967 | 0.701 | 0.337–1.458 | 0.342 |
Triple-negative vs Luminal A | 1.626 | 0.930–2.843 | 0.088 | 1.493 | 0.849–2.626 | 0.164 |
miR-223 | ||||||
low vs high | 3.960 | 2.201–7.126 | <0.001 | 3.789 | 2.098–6.843 | <0.001 |
CI, confidence interval; HR, hazard ratio.
The covariates in the Cox model were all categorical variables, and the adjusted p value and HR were derived from the model.
The p value of the univariate analysis is marked bold.