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. 2021 Apr 13;11:653902. doi: 10.3389/fonc.2021.653902

Figure 8.

Figure 8

(A) The relative level of miRNAs equals to the level of miRNAs in Fuc group divided by the level of miRNAs in Ctrl group. (B) The schematic of LINC00261 binds to miR-522-3p by base pairing. The examination of miR-522-3p level in MHCC-97H cells treated with saline (Ctrl), 0.25 mg/mL Fuc and 0.5 mg/mL Fuc. ** means P < 0.01, *** means P < 0.001. (C) The qPCR results of MHCC-97H cells transfected with miR-522-3p mimic and inhibitor. NC-M is short for negative control of miRNA mimic. NC-I is short for negative control of miRNA inhibitor. ** means P < 0.01, **** means P < 0.0001. (D) Relative cell proliferation rate of MHCC-97H cells transfected with miR-522-3p mimic and inhibitor. *** means P < 0.001. (E) Cell viability of MHCC-97H cells transfected with miR-522-3p mimic and inhibitor. ** means P < 0.01. (F) The cell viability of MHCC-97H cells in Ctrl group, 0.5 mg/mL Fuc treated group, 0.5 mg/mL Fuc treated and miR-522-3p mimic (miR-522-3p-M) transfected group. *** means P < 0.001. (G) Overexpression of miR-522-3p accelerates cell invasion of MHCC-97H cells. (H) Inhibition of miR-522-3p restrained cell invasion of MHCC-97H cells.