Table 4.
Effect of test diets on serum biochemical parameters
| Parameters | Control | NS50 | NS100 | NAS50 | NAS100 |
|---|---|---|---|---|---|
| Days | Fasting blood sugar (mg/dl) | ||||
| 45 | 73.0±5.12 | 86.0±6.53 | 81.43±8.55 | 87.5±6.86 | 85.33±5.01 |
| 90 | 67.17±1.74 | 63.83±2.36 | 62.8±5.12 | 70.17±4.43 | 74±5.122* |
| Serum cholesterol (mg/dl) | |||||
| 45 | 49.33±4.08 | 51.17±2.8 | 47.86±3.66 | 53.33±5.12 | 46.5±3.93 |
| 90 | 57.17±3.46 | 59.83±5.9 | 56.2±4.67 | 55.5±3.84 | 66.8±4.67 |
| Triglycerides (mg/dl) | |||||
| 45 | 208.67±29.13 | 220.0±19.41 | 185.14±19.54 | 130.67±24.22 | 88.17±20.68* |
| 90 | 69±5.70 | 74.17±3.31 | 87.6±8.76 | 68.67±11.33 | 80±8.76 |
| High-density lipoprotein (HDL) (mg/dl) | |||||
| 45 | 28.5±2.60 | 29.5±1.48 | 32.14±2.59 | 31.17±3.98 | 24.17±1.35 |
| 90 | 36.83±2.07 | 33.83±3.3 | 32.6±2.90 | 40.67±4.08 | 42.8±4.06 |
| Very low-density lipoprotein (LDL) (mg/dl) | |||||
| 45 | 41.83±5.79 | 43.83±4.00 | 37±3.87 | 26.17±4.83 | 17.67±4.13* |
| 90 | 13.77±1.13 | 15.67±1.45 | 17.4±3.41 | 13.83±2.30 | 12±3.41 |
| Serum glutamic pyruvic transaminase (SGPT) (IU/L) | |||||
| 45 | 55.67±4.77 | 43.33±5.8 | 57.71±4.53 | 62.5±3.65 | 57.67±6.04 |
| 90 | 56±7.93 | 46.33±4.82 | 35.8±3.87 | 75.5±15.69 | 61.2±3.87 |
| Serum glutamic oxaloacetic transaminase (SGOT) (IU/L) | |||||
| 45 | 125.17±7.24 | 120.33±6.83 | 129.14±5.53 | 136.17±5.21 | 142.17±29.37 |
| 90 | 118±4.47 | 137.17±11.59 | 110.4±9.64 | 150.67±8.90** | 161.6±9.64*** |
| Total bilirubin (mg/dl) | |||||
| 45 | 0.27±0.04 | 0.35±0.02 | 0.34±0.03 | 0.4±0.06 | 0.38±0.05 |
| 90 | 0.52±0.07 | 0.4±0.05 | 0.44±0.07 | 0.65±0.07 | 1.14±0.24* |
| Direct bilirubin (mg/dl) | |||||
| 45 | 0.12±0.02 | 0.15±0.02 | 0.16±0.02 | 0.12±0.02 | 0.13±0.02 |
| 90 | 0.21±0.03 | 0.17±0.03 | 0.28±0.10 | 0.25±0.05 | 0.2±0.10 |
| Blood urea (mg/dl) | |||||
| 45 | 29.67±2.499 | 35±1.9 | 36.14±2.04 | 33.17±3.439 | 33.67±1.256 |
| 90 | 48.67±2.84 | 42±2.30 | 45.8±3.12 | 40.67±0.80* | 40.2±3.12* |
| Serum creatinine (mg/dl) | |||||
| 45 | 0.72±0.12 | 0.98±0.05 | 1.07±0.29 | 0.88±0.05 | 0.93±0.02 |
| 90 | 0.7±0.04 | 0.6±0.06 | 0.82±0.07 | 0.77±0.05 | 0.84±0.04* |
| Total protein (g/dl) | |||||
| 45 | 6.08±0.21 | 6.13±0.14 | 6.59±0.29 | 6.88±0.18* | 6.32±0.15 |
| 90 | 6.11±0.28 | 5.85±0.28 | 5.62±0.18 | 6.78±0.44 | 6.44±0.18 |
| Albumin (g/dl) | |||||
| 45 | 3.3±0.19 | 3.72±0.17 | 3.57±0.11 | 3.82±0.21 | 3.03±0.08 |
| 90 | 3.23±0.13 | 3.18±0.18 | 3.08±0.224 | 3.43±0.17 | 3.54±0.22 |
| Globulin (g/dl) | |||||
| 45 | 2.78±0.16 | 2.42±0.22 | 2.59±0.21 | 3.07±0.09 | 3.28±0.16* |
| 90 | 2.36±0.24 | 2.67±0.12 | 2.54±0.12 | 2.95±0.54 | 2.9±0.12 |
| Uric acid (mg/dl) | |||||
| 45 | 0.87±0.19 | 0.8±0.16 | 0.86±0.07 | 0.95±0.11 | 1.23±0.14 |
| 90 | 0.9±0.08 | 0.93±0.03 | 1±0.05 | 0.77±0.08 | 1.2±0.05 |
| Serum calcium (mg/dl) | |||||
| 45 | 8.4±0.29 | 9.13±0.31 | 9.19±0.21 | 8.48±0.28 | 7.75±0.24 |
| 90 | 9.38±0.53 | 9.81±0.18 | 9.82±0.22 | 9.9±0.15 | 9.6±0.22 |
Data are presented as mean±SEM, *P<0.05, **P<0.01, ***P<0.001 compared to control group (paired t-test). SEM: Standard error of the mean