Table 3.
Effect of Comorbid Conditions on HAPI Occurrences
| Clinical Data | Category | HAPI (N = 165) |
Control (N = 310) |
Total (N = 475) |
P Value |
|---|---|---|---|---|---|
| Any type of dialysis | No | 118 (71.5%) | 296 (95.8%) | 414 (87.3%) | <.001 |
| Yes | 47 (28.5%) | 13 (4.2%) | 60 (12.7%) | ||
| Body Mass Index, Mean (SD) | 30.6 (12.1) | 30.6 (10.1) | 30.6 (10.9) | 0.987 | |
| Blood pH (lowest) , Mean (SD) | 7.3 (0.1) | 7.3 (0.1) | 7.3 (0.1) | 0.907 | |
| Bowel Management system | No | 131 (79.4%) | 282 (91.3%) | 413 (87.1%) | <.001 |
| Yes | 34 (20.6%) | 27 (8.7%) | 61 (12.9%) | ||
| Capillary refill > 3 seconds | No | 133 (84.7%) | 217 (89.3%) | 350 (87.5%) | 0.176 |
| Yes | 24 (15.3%) | 26 (10.7%) | 50 (12.5%) | ||
| Chemically Sedated (IV Drip) | No | 73 (44.2%) | 167 (53.9%) | 240 (50.5%) | 0.046 |
| Yes | 92 (55.8%) | 143 (46.1%) | 235 (49.5%) | ||
| Daily Weight (kg), Mean (SD) | 88.4 (32.5) | 89.3 (29.2) | 88.9 (30.5) | 0.803 | |
| FiO2a, Mean (SD) | 59.6 (27.7) | 52.3 (25.1) | 55.6 (26.5) | 0.008 | |
| Hemoglobin (lowest) , Mean (SD) | 7.9 (1.6) | 9.7 (2.1) | 9.1 (2.1) | <.001 | |
| MAP < 60 a | No | 65 (39.4%) | 166 (53.7%) | 231 (48.7%) | 0.003 |
| Yes | 100 (60.6%) | 143 (46.3%) | 243 (51.3%) | ||
| Mechanical Ventilation | No | 35 (21.2%) | 161 (51.9%) | 196 (41.3%) | <.001 |
| Yes | 130 (78.8%) | 149 (48.1%) | 279 (58.7%) | ||
| Moisture a | No | 74 (44.8%) | 273 (88.9%) | 347 (73.5%) | <.001 |
| Yes | 91 (55.2%) | 34 (11.1%) | 125 (26.5%) | ||
| O2 stat (lowest) , Mean (SD) | 87.8 (9.2) | 86.7 (12.7) | 87.1 (11.6) | 0.295 | |
| Paralytic Agent > 2 hrs | No | 148 (90.2%) | 260 (85.5%) | 408 (87.2%) | 0.145 |
| Yes | 16 (9.8%) | 44 (14.5%) | 60 (12.8%) | ||
| Periop/ Procedure > or = to 4 hr | No | 150 (90.9%) | 48 (84.2%) | 198 (89.2%) | 0.160 |
| Yes | 15 (9.1%) | 9 (15.8%) | 24 (10.8%) | ||
| SBP < 90 mmHg a | No | 59 (35.8%) | 25 (8.1%) | 84 (17.7%) | <.001 |
| Yes | 106 (64.2%) | 285 (91.9%) | 391 (82.3%) | ||
| Specialty bed type | No | 149 (90.3%) | 301 (97.7%) | 450 (95.1%) | <.001 |
| Yes | 16 (9.7%) | 7 (2.3%) | 23 (4.9%) | ||
| Steroids | No | 116 (70.3%) | 258 (83.2%) | 374 (78.7%) | 0.001 |
| Yes | 49 (29.7%) | 52 (16.8%) | 101 (21.3%) | ||
| Temperature (highest-Celsius), Mean (SD) | 38.0 (0.9) | 37.9 (0.8) | 38.0 (0.8) | 0.067 | |
| Temperature (lowest-Celsius), Mean (SD) | 35.9 (0.8) | 36.2 (0.8) | 36.1 (0.8) | 0.004 | |
| Unintentional Weight loss of 10 or more pounds in one month? | No Yes |
121 (73.3%) 20 (12.1%) |
198 (66.7%) 19 (6.4%) |
319 (69%) 39 (8.4%) |
0.002 |
| Vasopressors (concurrently) | No | 97 (58.8%) | 234 (75.5%) | 331 (69.7%) | <.001 |
| Yes | 68 (41.2%) | 76 (24.5%) | 144 (30.3%) | ||
| Waffle mattress | No | 145 (87.9%) | 300 (98.4%) | 445 (94.7%) | <.001 |
| Yes | 20 (12.1%) | 5 (1.6%) | 25 (5.3%) |
Note:
a.
Variables were included in multivariate logistic regression in Table 5.