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. 2021 Apr 15;17(4):e1009505. doi: 10.1371/journal.ppat.1009505

Fig 4. Ig production in PBMC or PBMC depleted of pDC after stimulation with I-TBEV.

Fig 4

Total PBMC or PBMC depleted of pDC (PBMC-pDC) were left untreated (NS) or stimulated with R848 (5 μM) and inactivated TBEV (I-TBEV) (dilution 1:12.5) for 10 days. The production of either total IgM (A) or IgG (B) was measured in culture supernatants by ELISA. The results shown were mean values ± SEM of 3 independent experiments. P-value for IgM: *p = 0.03; **p = 0.02.