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. 2021 Apr 27;16(4):e0250328. doi: 10.1371/journal.pone.0250328

Table 3. Prevalence of lipid abnormalities among patients receiving ART by types of ART regimen.

ART regimens TC ≥ 200 mg/dl TG ≥ 150 mg/dl HDL-c < 40 mg/dl LDL-c ≥ 130 mg/dl TC/HDL-c ratio ≥5
n = 185 (%) n = 121 (%) n = 76 (%) n = 116 (%) n = 54 (%)
NRTI regimens
    TDF-based 81 (49.1) 49 (29.7) 30 (18.2) 53 (32.6) 24 (14.5)
    AZT-based 76 (48.7) 50 (32.1) 32 (20.5) 45 (28.8) 21 (13.5)
    D4T-based 28 (39.4) 22 (31.0) 14 (19.7) 18 (25.4) 9 (12.7)
    P-value 0.350 0.901 0.867 0.560 0.920
NNRTI regimens
    NVP-based 103 (47.9) 65 (30.2) 40 (18.6) 67 (31.2) 26 (12.1)
    EFV-based 82 (48.3) 56 (31.6) 36 (20.3) 49 (27.7) 28 (15.8)
    P-value 0.755 0.764 0.666 0.453 0.287

ART, antiretroviral therapy; TC, total cholesterol; TG, triglyceride; HDL-c, high-density lipoprotein cholesterol; LDL-c, low-density lipoprotein cholesterol, NRTIs, nucleoside reverse transcriptase inhibitors; NNRTIs, nonnucleoside reverse transcriptase inhibitors; TDF, tenofovir; AZT, zidovudine; D4T, stavudine; EFV, efavirenz; NVP, nevirapine