Figure 3.
SS Rats and Increase in Fibrosis
SS rats demonstrate no appreciable increase in fibrosis 10 weeks after 24-Gy localized cardiac RT. Ten weeks after 24 Gy of localized cardiac RT or sham treatment, Masson’s trichrome staining was performed, and the interstitial and perivascular fibrosis was quantified. There was a nonsignificant increase in interstitial (A to C) and perivascular (D to F) fibrosis in the RT-treated hearts. n = 4 to 5/condition. Values are mean ± SEM; p = 0.476. Abbreviations as in Figure 1.