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. 2021 Mar 16;3(1):113–130. doi: 10.1016/j.jaccao.2020.12.006

Figure 6.

Figure 6

Strain Measurements in RT and Sham-Treated Rats

Strain measurements in radiation therapy (RT) and sham-treated rats reveal early worsening in strain, especially in the circumferential direction, post-RT. Compared with sham, circumferential strain changes occurred at the basal, mid-ventricular, and apical levels (p < 0.05 for all), especially at the lateral regions, which suggests that circumferential strain is a sensitive marker of RT-induced cardiotoxicity.