Strain Measurements in RT and Sham-Treated Rats
Strain measurements in radiation therapy (RT) and sham-treated rats reveal early worsening in strain, especially in the circumferential direction, post-RT. Compared with sham, circumferential strain changes occurred at the basal, mid-ventricular, and apical levels (p < 0.05 for all), especially at the lateral regions, which suggests that circumferential strain is a sensitive marker of RT-induced cardiotoxicity.