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. 2021 Mar 16;3(1):113–130. doi: 10.1016/j.jaccao.2020.12.006

Central Illustration.

Central Illustration

Strain Measurements in Radiation Therapy and Sham Rats

Strain measurements in radiation therapy (RT) and sham rats reveal early worsening in strain, especially in the circumferential direction, post-RT. Compared with sham treatment, circumferential strain changes occurred at the basal, mid-ventricular, and apical levels (p < 0.05 for all), especially at the lateral regions, which suggests that circumferential strain a sensitive marker of RT-induced cardiotoxicity.