Strain Measurements in Radiation Therapy and Sham Rats
Strain measurements in radiation therapy (RT) and sham rats reveal early worsening in strain, especially in the circumferential direction, post-RT. Compared with sham treatment, circumferential strain changes occurred at the basal, mid-ventricular, and apical levels (p < 0.05 for all), especially at the lateral regions, which suggests that circumferential strain a sensitive marker of RT-induced cardiotoxicity.