Table 1.

Global Cardiac Function Parameters at Different Time Points Post-RT

	8 Weeks			10 Weeks
	Sham-Treated Controls	Post-RT	p Value vs. Control	Post-RT	p Value vs. Control
LV EF, %	67.0 ± 2.6	78.0 ± 0.7	0.003	79.0 ± 0.9	0.002
LV mass, g	0.38 ± 0.01	0.49 ± 0.02	<0.001	0.56 ± 0.01	<0.001
LV EDV, ml	0.29 ± 0.01	0.259 ± 0.010	0.022	0.263 ± 0.010	0.014
LV ESV, ml	0.10 ± 0.007	0.060 ± 0.004	<0.001	0.060 ± 0.003	<0.001
LV SV, ml	0.190 ± 0.008	0.200 ± 0.007	0.317	0.200± 0.005	0.141
RV EF, %	69.0 ± 1.2	73.0 ± 1.6	0.039	72.0 ± 1.6	0.038
RV mass, g	0.070 ± 0.002	0.100 ± 0.009	0.009	0.130 ± 0.008	<0.001
RV EDV, ml	0.140 ± 0.005	0.120 ± 0.008	0.113	0.130 ± 0.009	0.300
RV ESV, ml	0.040 ± 0.003	0.030 ± 0.002	0.007	0.030 ± 0.004	0.047
RV SV, ml	0.100 ± 0.005	0.090 ± 0.007	0.639	0.100 ± 0.006	0.556

Values are mean ± SEM.

EDV = end-diastolic volume; EF = ejection fraction; ESV = end-systolic volume; LV = left ventricular; RT = radiation therapy; RV = right ventricular; SV = stroke volume.