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. Author manuscript; available in PMC: 2021 Apr 27.
Published in final edited form as: Nanotechnol Rev. 2020 Dec 31;9(1):1500–1521. doi: 10.1515/ntrev-2020-0117

Table 1:

Chemical compounds used in SC and their biopathway inhibitors’ molecular targets

Inhibitor Pathway Gene References
Vemurafenib BRAF RAS/MAPK [199]
Dabrafenib [200]
Encorafenib [201]
Trametinib MEK MAPK/ERK [202]
Cobimetinib [203]
Binimetinib [204]
Ipilimumab CTLA4 Immune Chk [205]
Nivolumab [206]
Pembrolizumab PDLI PD1 [207]
Cemiplimab [59]
Itraconazole SMO Hedgehog [56]
Sonidegib [57]
Vismodegib [55]