Table 3.

Multivariate Cox regression analysis.

Predictors on admission	Univariable analysis; HR (95% CI)	P	Multivariable analysis; HR (95% CI)	P
Sex	1.108 (0.787–1.562)	0.556
Age (per year)	1.080 (1.063–1.097)	< 0.001	1.069 (1.051–1.087)	< 0.001
Myocardial injury	4.355 (3.112–6.093)	< 0.001	1.716 (1.182–2.492)	0.005
Hypertension	1.960 (1.380–2.784)	< 0.001
RAAS inhibitors use	1.700 (1.210–2.388)	0.002
Hematocrit (per % decrease)	0.929 (0.905–0.954)	< 0.001
Creatinine (per mg/dL)	1.469 (1.304–1.655)	< 0.001	1.291 (1.103–1.511)	< 0.001
D-Dimer (per ng/mL)	1.011 (0.986–1.036)	0.390
C-reactive protein (per mg/L)	1.002 (1.002–1.003)	< 0.001	1.002 (1.001–1.003)	< 0.001
CCI (per point increase)	1.274 (1.216–1.335)	< 0.001

CCI — Charlson comorbidity index; CI — confidence interval; HR — hazard ratio; RAAS — renin–angiotensin–aldosterone system