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. 2021 Apr 26;36(1):940–953. doi: 10.1080/14756366.2021.1875459

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© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Inhibition of COX-1 and COX-2 by Flu-AM4. Inhibition of the activities of ovine COX-1 (towards arachidonic acid, AA) and human recombinant COX-2 (towards either arachidonic acid or 2-AG) by Flu-AM4. Shown are means ± s.e.m., n = 3 for the change in oxygen tension following addition of enzyme in the presence of the concentrations of the compounds (µM) shown on the right of each panel. The enzyme isoform and substrate (10 μM concentration) used are shown above each panel. “F” in Panel A refers to 10 µM flurbiprofen, used as a positive control for COX-1.