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Effect of vehicle and Flu-AM4 in CCI-induced mechanical (A) and hyperalgesia (B) allodynia on day 7 and 14. Mice 1 h before test were treated with vehicle (grey bars) and Flu-AM4 (1, 3 or 10 mg/kg ip). Data are shown as mean ± SEM of 6 animals per group. *p < 0.05 and p < 0.01 vs. vehicle, 2-way repeated-measures ANOVA with post-hoc Bonferroni tests.
