Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
pI50 (-logIC50) and the derived IC50 values for inhibition of rat brain AEA hydrolysis by flurbiprofen amides. In all cases, the maximum inhibition was 100%.
| Compound | pI50 | IC50 (µM) | |
|---|---|---|---|
| Flurbiprofena | 4.53 ± 0.02 | 29 | |
| Flu-AM1a |  |
6.36 ± 0.02 | 0.44 |
| Flu-AM3 |  |
6.96 ± 0.12 | 0.11 |
| Flu-AM4 |  |
7.67 ± 0.10 | 0.021 |
| Flu-AM6 |  |
7.72 ± 0.07 | 0.019 |
aThe data for flurbiprofen and Flu-AM1, shown for comparative purposes, are from Ref. 26. Data are means ± s.e.m., n = 3–4.
