Table 2.
Pathways significantly altered by the DEGs in treated samples.
| Category | Term | Description | Count | P |
|---|---|---|---|---|
| Up-regulated DEGs | ||||
| KEGG | hsa00010 | Glycolysis/Gluconeogenesis | 15 | 3.66E-12 |
| KEGG | hsa00051 | Fructose and mannose metabolism | 6 | 4.49E-04 |
| KEGG | hsa00330 | Arginine and proline metabolism | 7 | 5.12E-04 |
| KEGG | hsa00500 | Starch and sucrose metabolism | 6 | 1.21E-03 |
| KEGG | hsa00030 | Pentose phosphate pathway | 5 | 1.25E-03 |
| KEGG | hsa04810 | Regulation of actin cytoskeleton | 12 | 2.84E-03 |
| KEGG | hsa04510 | Focal adhesion | 10 | 1.57E-02 |
| KEGG | hsa00270 | Cysteine and methionine metabolism | 4 | 2.77E-02 |
| KEGG | hsa05012 | Parkinson’s disease | 7 | 3.78E-02 |
| KEGG | hsa04610 | Complement and coagulation cascades | 5 | 4.46E-02 |
| KEGG | hsa05211 | Renal cell carcinoma | 5 | 4.67E-02 |
| Down-regulated DEGs | ||||
| KEGG | hsa00970 | Aminoacyl-tRNA biosynthesis | 7 | 2.92E-05 |
| KEGG | hsa00330 | Arginine and proline metabolism | 4 | 4.56E-02 |
DEG — differentially expressed genes; KEGG — Kyoto Encyclopedia of Genes and Genomes; Count — gene numbers enriched in a specific biological process term