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. 2021 Apr 13;12:618724. doi: 10.3389/fphar.2021.618724

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Copyright © 2021 Fan, Liu, Zhang, Su, Yuan, Lin, Yang, Li and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Masson staining and immunohistochemical staining for OCN and CD31 in the bone defect area at the 8th week; FT indicates “fiber texture”, and BT indicates “bone tissue”. The values are represented as the mean ± SD (n = 6).