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. 2021 Apr 27;10:e60824. doi: 10.7554/eLife.60824

Figure 7. Changes in thalamo-cortical phase synchronization during Awake vs. Unconscious states.

(A-D) (Left subpanels) Change in the pairwise phase consistency (PPC) for all time points relative to loss of consciousness (LOC) compared to Awake (−15 to −10 min pre-LOC). The red vertical lines indicate the average ± 1 standard deviation time of propofol onset. The black vertical line indicates time zero (LOC). Significant increases or decreases (p<0.01, corrected for multiple comparisons) from Awake are marked with opaque colors and are highlighted. (Right subpanels) Same as left subpanels but time-locked to recovery of consciousness (ROC). The red vertical lines indicate the average ± 1 standard deviation time of propofol offset. The black vertical line indicates time zero (ROC). Significant increases or decreases from Awake are opaque colors and are highlighted. PFC: ventrolateral prefrontal cortex; 8A: caudal lateral PFC; PPC: posterior parietal cortex area 7A/7B; STG: superior temporal gyrus.

Figure 7.

Figure 7—figure supplement 1. Effect sizes for change in thalamo-cortical phase synchronization during Awake vs. Unconscious states (left panels).

Figure 7—figure supplement 1.

Average pairwise phase consistency (PPC) during the Awake (blue) vs. Unconscious (red) states. (Right subpanels) Average PPC difference (Unconscious – Awake). Mean is displayed in bold lines and the 99 percent bootstrap confidence interval of the mean is shown in dotted lines. PFC: ventrolateral prefrontal cortex; 8A: caudal lateral PFC; PPC: posterior parietal cortex area 7A/7B; STG: superior temporal gyrus.