Table 1. Return to Wakefulness (RTW) scores for effects of high-current thalamic stimulation on physiological measures of arousal, firing rates, and cortical power.

Measure	Awake	Pre-stim unconscious	Stim	Post-stim1	Post-stim2	Post-stim3
EMG variance	−100%	0%	−2% (ns)	0% (ns)	0% (ns)	0% (ns)
Eyeblinks	−100%	0%	−36% (*)	−32% (*)	−7% (ns)	−2% (ns)
Blood oxygenation	−100%	0%	−1% (ns)	−69% (*)	−48% (*)	−19% (ns)
Heart rate	−100%	0%	−328% (*)	−362% (*)	−109% (ns)	−64% (ns)
Firing rate (PFC)	−100%	0%	−6% (ns)	−16% (*)	−9% (ns)	−4% (ns)
Firing rate (8A)	−100%	0%	−10% (ns)	−13% (ns)	−8% (ns)	−4% (ns)
Firing rate (PPC)	−100%	0%	−33% (*)	−18% (*)	−11% (ns)	−6% (ns)
Firing rate (STG)	−100%	0%	−26% (*)	−15% (ns)	−6% (ns)	−3% (ns)
Slow frequency power (PFC)	−100%	0%	−45% (*)	−19% (*)	−11% (ns)	−6% (ns)
Slow frequency power(8A)	−100%	0%	−65% (*)	−31% (*)	−18% (*)	−10% (*)
Slow frequency power (PPC)	−100%	0%	−44% (*)	−7% (*)	−1% (ns)	−1% (ns)
Slow frequency power (STG)	−100%	0%	−89% (*)	−8% (ns)	2% (ns)	1% (ns)
Beta power (PFC)	−100%	0%	400% (*)	1071% (*)	799% (*)	449% (*)
Beta power (8A)	−100%	0%	−265% (*)	−228% (*)	−153% (*)	−88% (*)
Beta power (PPC)	−100%	0%	−27% (*)	−29% (*)	−23% (*)	−17% (*)
Beta power (STG)	−100%	0%	−24% (*)	−44% (*)	−31% (*)	−16% (*)
Gamma power (PFC)	−100%	0%	−47% (*)	−48% (*)	−26% (*)	−12% (*)
Gamma power (8A)	−100%	0%	−59% (*)	−40% (*)	−22% (*)	−11% (*)
Gamma power (PPC)	−100%	0%	−71% (*)	−45% (*)	−27% (*)	−15% (*)
Gamma power (STG)	−100%	0%	−77% (*)	−43% (*)	−19% (*)	−6% (ns)

Asterisks denote significant (p<0.01) changes from the Unconscious state.

PFC: prefrontal cortex; PPC: posterior parietal cortex 7A/7B; 8A: caudal lateral PFC; STG: superior temporal gyrus.