Table 2. Return to Wakefulness (RTW) scores for effects of high-current thalamic stimulation on LFP-LFP and spike-LFP slow-frequency phase synchronization.
| Measure | Awake | Pre-stim unconscious | Stim | Post-stim1 | Post-stim2 | Post-stim3 |
|---|---|---|---|---|---|---|
| Spike-LFP (PFC) | −100% | 0% | −24% (*) | 15% (ns) | −1% (ns) | 1% (ns) |
| Spike-LFP (8A) |
−100% | 0% | 103% (*) | 96% (*) | 79% (*) | 38% (ns) |
| Spike-LFP (PPC) | −100% | 0% | −35% (*) | −8% (ns) | 6% (ns) | 12% (*) |
| Spike-LFP (STG) | −100% | 0% | −113% (*) | −16% (ns) | 24% (ns) | 29% (ns) |
| LFP-LFP (PFC-thalamus) |
−100% | 0% | −77% (*) | −58% (*) | −7% (ns) | 8% (ns) |
| LFP-LFP (8A-thalamus) |
−100% | 0% | −77% (*) | −71% (*) | −16% (ns) | −4% (ns) |
| LFP-LFP (PPC-thalamus) |
−100% | 0% | −10% (ns) | −19% (ns) | 30% (ns) | 15% (ns) |
| LFP-LFP (STG-thalamus) |
−100% | 0% | −71% (*) | −68% (*) | −27% (*) | −12% (ns) |
| LFP-LFP (PFC-8A) | −100% | 0% | −40% (*) | −25% (*) | −6% (ns) | 3% (ns) |
| LFP-LFP (PFC-PPC) | −100% | 0% | −60% (*) | 3% (ns) | 17% (ns) | 1% (ns) |
| LFP-LFP (PFC-STG) | −100% | 0% | −45% (*) | −11% (ns) | 6% (ns) | 36% (*) |
| LFP-LFP (8A-PPC) | −100% | 0% | −29% (*) | −13% (ns) | −7% (ns) | 8% (ns) |
| LFP-LFP (8A-STG) | −100% | 0% | −63% (*) | −41% (*) | −8% (ns) | 11% (ns) |
| LFP-LFP (PPC-STG) | −100% | 0% | 29% (*) | 5% (ns) | 9% (ns) | 4% (ns) |
Asterisks denote significant (p<0.01) changes from the Unconscious state.
PFC: prefrontal cortex; PPC: posterior parietal cortex 7A/7B; 8A: caudal lateral PFC; STG: superior temporal gyrus; LFP: local field potentials. .