Table 1:

Pertinent Baseline Characteristics of the Women (N =263)

Age, years (mean±SD)	54±11
Body mass index, kg/m2 (mean±SD)	29±7
History of:
- Diabetes, n (%)	27 (10%)
- Hypertension, n (%)	115 (44%)
- Dyslipidemia, n (%)	63 (24%)
- Smoking, n (%)	91 (35%)
- Family history of CAD, n (%)	108 (41%)
- Pregnancy, n (%)	206 (78%)
Current use of hormonal replacement therapy, n (%)	39 (15%)
- u-hscTnI (ng/L), median (IQR)	0.81 (0.44-1.52)
Medications
- Beta blockers, n (%)	63 (24%)
- ACEI/ARB, n (%)	59 (22%)
- CCB, n (%)	41 (16%)
- Statins, n (%)	85 (32%)
Coronary vascular function measures
- Coronary flow reserve, median (IQR)	2.7 (2.3-3.0)
- Limited coronary flow reserve, N (%)	74 (30%)
- CBF in response to IC-ACH (%), median (IQR)	38.6 (6.5-100.4)
- Limited CBF, N (%)	107 (55%)
- Coronary diameter dilation in response to IC-ACH (%), median (IQR)	1.02 (−7.1-9.2)
- Limited coronary epicardial constriction in response to IC-ACH, N (%)	105 (46%)
- Coronary diameter dilation in response to IC-NTG (%), median (IQR)	15 (6.0-24.1)
- Limited coronary epicardial dilation in response to IC-NTG, N (%)	144 (64)

SD: standard deviation, u-hscTnI: ultra-high sensitivity troponin, IQR: interquartile range, ACEI: angiotensin converting enzyme inhibitor, ARB: angiotensin-receptor blocker, CBF: coronary blood flow, IC-ACH: intra-coronary acetylcholine, IC-NTG: intra-coronary nitroglycerin. Normal coronary flow reserve ≥2.32, Normal coronary blood flow (CBF) ≥50%, normal coronary epicardial diameter change in response to IC-ACH ≥0% and normal coronary epicardial diameter change in response to IC-NTG ≥20%.