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. Author manuscript; available in PMC: 2021 Jul 10.
Published in final edited form as: J Control Release. 2020 Apr 6;323:240–252. doi: 10.1016/j.jconrel.2020.03.040

Figure 3.

Figure 3.

DNA nanostructure-based DDS for the delivery of oligonucleotides. (a) DNA tetrahedron nanoparticles for siRNA delivery. Reproduced with permission from ref 59. Copyright 20012 Nature Publishing Group. (b) Protection and delivery of miRNA via Shuriken-like DNA structures. Reproduced from ref. 60 with permission from the Royal Society of Chemistry. (c) DNA tube- and (d) dendrimer-based delivery of CpG DNA strands. Reproduced with permissions from refs 63 and 64. Copyright 2011 and 2015 American Chemical Society. (e) DNA-scaff olded adjuvant-antigen vaccine complex. Reproduced with permission from ref. 66. Copyright 2012 American Chemical Society.