Table 1.
Analysis of demographic situation of the POPH group and non-POPH group.
| Variables | POPH (n = 28) | Non-POPH (n = 160) | χ 2/t | P |
|---|---|---|---|---|
| Age (years) | 63 ± 8 | 59 ± 11 | -1.541 | 0.125 |
| Gender N (%) | ||||
| Male | 12 (42.9) | 110 (68.7) | 7.017 | <0.01 |
| Female | 16 (57.1) | 50 (31.3) | ||
| Etiology N (%) | ||||
| HBV | 10 (35.7) | 71 (44.4) | 0.729 | 0.393 |
| HCV | 2 (7.1) | 21 (13.1) | — | 0.537 |
| Alcohol | 9 (32.1) | 37 (23.1) | 1.049 | 0.306 |
| Drug | 1 (3.6) | 6 (3.8) | — | 1.00 |
| Autoimmune | 3 (10.7) | 14 (8.8) | — | 0.723 |
| Liver cancer N (%) | ||||
| Yes | 4 (14.3) | 51 (31.9) | 3.562 | 0.059 |
| No | 24 (85.7) | 109 (68.1) | ||
| Hypertension N (%) | ||||
| Yes | 5 (17.9) | 22 (13.7) | — | 0.563 |
| No | 23 (82.1) | 138 (86.3) | ||
| Diabetes N (%) | ||||
| Yes | 3 (10.7) | 30 (18.8) | — | 0.422 |
| No | 25 (89.3) | 130 (81.3) | ||
| Splenectomy N (%) | ||||
| Yes | 6 (21.4) | 21 (13.1) | — | 0. 249 |
| No | 22 (78.6) | 139 (86.9) | ||
| Portal vein thrombosis N (%) | ||||
| Yes | 4 (14.3) | 21 (13.1) | — | 0.771 |
| No | 24 (85.7) | 139 (86.9) | ||
The diagnosis of portal hypertension in this study is based on the 2016 Practice Guidance by the AASLD on Portal Hypertensive Bleeding in Cirrhosis [9]. All patients had manifestations of liver cirrhosis and portal hypertension confirmed by abdominal imaging (ultrasound, CT, or MRI), and most patients had complications of portal hypertension at the time of admission, such as portal hypertensive bleeding and ascites.