Table 1.
Factor loading values for principal components 1–5 for all MEA parameters analyzed.
| Parameter | PC1 | PC2 | PC3 | PC4 | PC5 |
|---|---|---|---|---|---|
| Burst percentage—Avg | 0.938953 | − 0.21655 | − 0.09068 | 0.095365 | − 0.03905 |
| Network burst percentage | 0.930335 | − 0.16411 | − 0.03479 | − 0.00912 | 0.030603 |
| Number of spikes per burst—Avg | 0.927633 | − 0.07813 | 0.131878 | 0.180872 | − 0.20604 |
| Number of bursting electrodes | 0.924737 | 0.11382 | − 0.13932 | − 0.05683 | − 0.03851 |
| Number of spikes per network burst per channel—Avg | 0.916818 | − 0.09696 | 0.059892 | − 0.0695 | − 0.30286 |
| Synchrony index | 0.91299 | − 0.25337 | − 0.09404 | 0.126219 | − 0.03106 |
| Number of spikes per network burst—Avg | 0.90668 | − 0.14074 | 0.063698 | − 0.03136 | − 0.3157 |
| ISI coefficient of variation—Avg | 0.875459 | − 0.13787 | − 0.14411 | 0.203831 | − 0.09526 |
| Area under normalized cross-correlation | 0.866748 | − 0.32439 | − 0.0838 | 0.14749 | − 0.01187 |
| Number of elecs participating in burst—Avg | 0.866593 | 0.127533 | − 0.16016 | − 0.10207 | − 0.04436 |
| Mean firing rate (Hz) | 0.787233 | − 0.09261 | 0.483835 | − 0.01736 | 0.111684 |
| Network IBI coefficient of variation | 0.739427 | 0.22799 | − 0.36458 | − 0.23674 | 0.12618 |
| Burst duration—Avg (s) | 0.730618 | 0.521412 | 0.032794 | 0.197191 | − 0.12086 |
| Normalized duration IQR—Avg | 0.707402 | 0.327012 | − 0.30471 | 0.026697 | 0.337296 |
| IBI coefficient of variation—Avg | 0.64845 | 0.459111 | − 0.30775 | 0.114136 | 0.20907 |
| Network normalized duration IQR | 0.613893 | 0.064961 | − 0.38534 | − 0.17934 | 0.144007 |
| Area under cross-correlation | 0.606648 | − 0.40216 | 0.517657 | 0.237669 | − 0.14355 |
| Burst frequency—Avg (Hz) | 0.592944 | − 0.04631 | 0.437397 | 0.034638 | 0.423479 |
| Network burst frequency (Hz) | 0.506543 | − 0.0198 | 0.364146 | − 0.01999 | 0.590348 |
| Network burst duration—Avg (s) | 0.490791 | 0.412156 | 0.078862 | − 0.54881 | − 0.07344 |
| Width at half height of cross-correlation | 0.233083 | 0.626106 | 0.385101 | − 0.42764 | − 0.13819 |
| Width at half height of normalized cross-correlation | 0.175127 | 0.727927 | 0.205821 | − 0.28793 | − 0.18294 |
| Mean ISI within burst—Avg | 0.029257 | 0.891807 | 0.112554 | 0.360375 | 0.016162 |
| Median ISI within burst—Avg | − 0.05205 | 0.881542 | 0.1378 | 0.359244 | 0.017994 |
| Inter-burst interval—Avg (s) | − 0.27591 | 0.571143 | − 0.11858 | 0.370944 | − 0.15048 |
Parameters sorted by descending PC1 loading value.